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The first GWAS of Global Electrical Heterogeneity ECG phenotype


Our manuscript is published today in JAHA. Uncovering mechanisms behind Global Electrical Heterogeneity: mechanisms of ventricular conduction abnormalities, left-to-right asymmetry, and more: 10 independent genetic loci identified. Specific “electrical signatures”—a specific pattern of associations with the GEH ECG phenotype is suggesting variable underlying biological and electrophysiological phenomena underlying each locus, which reflects multifactorial nature of GEH.


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