Search
  • Admin

Plasticizer Interaction With the Heart: Chemicals Used in Plastic Medical Devices Can Interfere With


Our collaborative work with Dr.Nikki Posnack is published in Circulation EP!

Main findings:

- Acute phthalate exposure slowed atrioventricular conduction and increased atrioventricular node effective refractory period in an intact, whole heart model. - Phthalate exposure prolonged action potential duration time, enhanced action potential triangulation, and increased the ventricular effective refractory period. - Phthalate exposure slowed epicardial conduction velocity, which may be partly explained by inhibition of Nav1.5

This important work shade the light on mechanisms of sudden cardiac death in end-stage kidney disease patients undergoing dialysis.


21 views

Recent Posts

See All

Cardiac memory in ICD patients

Our manuscript is accepted for publication. Stay tuned for more details! We described a saturation effect in cardiac memory development, sex differences in cardiac memory, and "activation memory" phen

3181 SW Sam Jackson Park Rd

Portland, OR, 97239

503-494-2374

© 2017 by Larisa Tereshchenko

  • Twitter Social Icon