Cardiac memory in ICD patients

Our manuscript is published in the Journal of Innovations in Cardiac Rhythm Management. We described: (1) a saturation effect in cardiac memory development, (2) sex differences in cardiac memory, and (3) "activation memory" phenomenon (in addition to "repolarization memory"). Repolarization memory manifests by TAAI-7 vector aligning with altered activation (QRS) vector; repolarization “remembers” abnormal activation. In turn, activation memory manifests during continued altered activation by altered activation vector striving to align with the baseline (before-VP) activation vector. Activation memory is likely a compensatory mechanism attempting to minimize dyssynchrony developing in response to sustained altered activation.