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October 23, 2019

Our manuscript is accepted for publication! It is published 11/14/19 in the BMC Cardiovascular Disorders!

Short-term and long-term predictive accuracy of ECG biomarkers of SCD differed, reflecting differences in transient vs. persistent SCD substrates.  The dynamic predictive accuracy of ECG biomarkers should be considered for competing SCD risk scores. The distinction between markers predicting short-term and long-term events may represent the difference between markers heralding SCD (triggers or transient substrates) versus markers identifying persistent substrate. 

September 20, 2019

Our collaborative paper with Dr. Jonathan Waks' team is now in press in Heart Rhythm!  AADs change GEH measurements. These changes, which differ by gender, are likely driven by alterations in ion-channel function and dispersion of depolarization or repolarization. GEH measurement may allow early assessment of favorable or adverse AAD effects. 

September 8, 2019

Dr. Stacey Howell, MD, OHSU Cardiology Fellow,  presented results of our GEH study  in Paris, at the European Society of Cardiology meeting 2019.

August 25, 2019

Our manuscript is published in the Journal of American Heart Association.    

Our study showed several novel findings:

- Nonsustained ventricular tachycardia is more frequent during hemodialysis or within 6 hours post-hemodialysis.

-  In incident hemodialysis patients, heart rate sharply increases before nonsustained ventricular tachycardia events, suggesting a triggered ventricular tachycardia mechanism.

-  Every‐other‐day hemodialysis preserves physiological circadian rhythm in heart rate and heart rate variability, whereas the extension of the interdialytic period for the second day abolishes circadian rhythm and shows a steady deterioration in autonomic disbalance.

-  The harmful effect of the 2‐day interval without hemodialysis suggests that more frequent dialysis should be considered the preferred prescribed treatment schedule.

Improvement of patient adherence—avoiding missing hemodialysis sessions—can improve patient outcomes.

-  Diagnosis of autonomic imbalance in end‐stage...

August 6, 2019

Two abstracts of the Tereshchenko lab members were accepted for the presentations at AHA SS in Philadelphia!!! Congratulations to Kazi and Ashley! We are looking forward to reporting results of our studies at the major cardiovascular meeting! 

Stay tuned for more details!  

June 28, 2019

Our collaborative work with Dr.Nikki Posnack  is published in Circulation EP!

Main findings:

- Acute phthalate exposure slowed atrioventricular conduction and increased atrioventricular node effective refractory period in an intact, whole heart
model.
- Phthalate exposure prolonged action potential duration time, enhanced action potential triangulation, and increased the ventricular effective refractory period.
- Phthalate exposure slowed epicardial conduction velocity, which may be partly explained by inhibition of Nav1.5

This important work shade the light on mechanisms of sudden cardiac death in end-stage kidney disease patients  undergoing dialysis. 

May 22, 2019

Dr. Tereshchenko organized invited session on clinician-reported outcomes. Session was well attended and attracted good questions and attention of attendees. We had excellent speakers! 

May 22, 2019

 Dr. Kazi Haq presented our work on pacing spikes removal. Presentation was extremely successful and received great attention. Thanks Kazi for great work!!!

May 13, 2019

Dr. Stacey Howell, MD, OHSU Cardiology fellow, presented our poster "Hemodialysis  Triggers Autonomic Imbalance & Cardiac Arrhythmias: Insights from Continuous 14-day ECG Monitoring". Dr. Larisa Tereshchenko delivered invited talk "Optimization of the Surface ECG:The Origin of the Heart Vector". 

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Larisa Tereshchenko and her team received prestigious NIH R56 award to continue study of sudden cardiac death. We will continue study of global electr...

Larisa Tereshchenko and her team received NIH R56 award to continue study of sudden cardiac death

October 13, 2018

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Portland, OR, 97239

503-494-2374

© 2017 by Larisa Tereshchenko

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