Major Projects & Funding
We are immensely grateful for the past and current support of our research projects by the NIH, American Heart Association, Cleveland Clinic, OHSU, JHU, and philanthropic support. We are committed to our mission, asking important clinical questions focused on improving human health. Our research is solely funded through grants.
NHLBI R01-R56. Novel ECG Measures and risk of Sudden Cardiac Death
This ancillary ARIC and CHS study has 3 goals: (1) discovery of novel SCD mechanisms in the general population and development of novel mechanistic ECG risk markers of SCD; (2) development and validation of the novel resting 12-lead ECG risk score of SCD risk in the analysis of community-dwelling cohorts of adults, and (3) discovery of genetic loci associated with the novel mechanistic ECG phenotypes
American Heart Association Grant-In-Aid. Global Electrical Heterogeneity and Clinical Outcomes
This retrospective multicenter cohort will validate an independent association of electrocardiographic (ECG) global electrical heterogeneity (GEH) measures with sustained ventricular tachyarrhythmias and appropriate ICD therapies in systolic heart failure patients with primary prevention ICD, and will validate and re-calibrate GEH ECG risk score for prediction of sustained ventricular tachyarrhythmias and appropriate ICD therapies in systolic heart failure patients with primary prevention ICD.